منابع مشابه
Alterations of Heparan Sulfate Proteoglycans in Cancer
Heparan sulfate proteoglycans (HSPGs) are glycoproteins, with the common characteristic of containing covalently attached heparan sulfate glycosaminoglycan chains (GAGs). These molecules are highly modified in cancer, contributing to tumorigenesis. In fact, the expression of HSPGs is markedly altered during malignant transformation and tumor progression, affecting both the PG core proteins and ...
متن کاملProteoglycans—Biomarkers and Targets in Cancer Therapy
Proteoglycans (PGs), important constituents of the extracellular matrix, have been associated with cancer pathogenesis. Their unique structure consisting of a protein core and glycosaminoglycan chains endowed with fine modifications constitutes these molecules as capable cellular effectors important for homeostasis and contributing to disease progression. Indeed, differential expression of PGs ...
متن کاملProteoglycans in Chronic Liver Disease and Hepatocellular Carcinoma: An Update
The last four decades witnessed a brilliant career of proteoglycans (PGs). Once regarded as mere space-fillers or passive structural components of matrices and charge-selective barriers, these fascinating molecules have been increasingly acknowledged as key players in cell-cell and cell-matrix communication, and have become recognized as modulators of most, if not all, aspects of cell behavior ...
متن کاملEpidemiology and trends in mortality from liver cancer in Iran
Liver cancer is the sixth most common cancer worldwide and the third leading cause of death from cancer. Liver cancer is more prevalent in countries in East Asia, Southeast Asia and the western Central Africa.1 Liver cancer rates in North America and Western Europe, less than 10 cases per hundred thousand people in Asia and Africa between 50-150 cases per hundred thousand people.2 The inc...
متن کاملPrevalence of Fatty Liver in Breast Cancer Patients Undergoing Treatment
Background and purpose: Fatty liver is one of the most common liver diseases. Some treatments used in breast cancer may be associated with development of fatty liver. The present study aimed at investigating the prevalence of fatty liver in breast cancer patients. Materials and methods: In this cross-sectional study, 117 patients with breast cancer attending Ramsar Imam Sajjad Hospital in 2017...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2016
ISSN: 1007-9327
DOI: 10.3748/wjg.v22.i1.379